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INHIBITOR OF APOPTOSIS PROTEINS
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DeCS
Descriptor
English
:
Inhibitor of Apoptosis Proteins
Descriptor
Spanish
:
Inhibidor de las Proteínas de la Apoptosis
Descriptor
Portuguese
:
Proteínas Inibidoras de Apoptose
Tree Number:
D12.644.360.075.437
D12.776.476.075.437
Definition
English
:
A conserved class of
proteins
that
control
APOPTOSIS
in both
VERTEBRATES
and
INVERTEBRATES
. IAP
proteins
interact with and inhibit
CASPASES
, and they function as ANTI-APOPTOTIC
PROTEINS
. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of
apoptosis
repeat.
Indexing Annotation
English
:
APOPTOSIS REGULATORY PROTEINS
is also available
Pharmacological Action:
Caspase Inhibitors
History Note
English
:
2006(1997)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50802
Unique Identifier:
D051034
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS